Hagai Abeliovich

Selected publications

1) Journo, D., Winter, G., and H. Abeliovich (2008). Monitoring autophagy in yeast using FM 4–64 fluorescence. Methods Enzymol., in press.

2) Winter, G., Hazan, R., Bakalinsky, A., and H. Abeliovich (2008). Caffeine induces macroautophagy and confers a cytocidal effect on food spoilage yeast in combination with benzoic acid. Autophagy 4: 28–36.

3) Abeliovich, H.. (2007). Mitophagy: The life–or–death dichotomy includes yeast. Autophagy 3(3):275–277.

4) Tal, R., Winter, G., Ecker, N., Klionsky, D.J., and H. Abeliovich (2007). Aup1p, a yeast mitochondrial protein phosphatase homolog, is required for efficient stationary phase mitophagy and cell survival. J. Biol. Chem. 282:5617–5624.

5) Farhi, M., Dudareva, N., Weiss, D., Vainstein, A., and H. Abeliovich (2006). Synthesis of the food flavoring methyl benzoate by genetically engineered Saccharomyces cerevisiae. J. Biotechnol., 122: 307–315.

6) Baxter, B.K. Abeliovich, H., Zhang, X., Stirling, A.G., Burlingame, A.L., and D.S. Goldfarb (2005). Atg19p ubiquitination and the cytoplasm to vacuole trafficking pathway in yeast. J. Biol. Chem. 280: 39067–39076.

7) Abeliovich, H. (2005). An Empirical Extremum Principle for the Hill Coefficient in Ligand–Protein Interactions Showing Negative Co–operativity. Biophys. J., 89:76–79.

8) Hazan, R., Levine, A. and H. Abeliovich (2004). Selective effects of the food preservative benzoic acid on intracellular protein trafficking in S. cerevisiae. Applied and Environmental Microbiology, 70(8):4449–4457.

9) Reggiori F., Wang C.W., Nair U., Shintani T., Abeliovich H., Klionsky D.J. (2004). Early stages of the secretory pathway, but not endosomes, are required for Cvt vesicle and autophagosome assembly in Saccharomyces cerevisiae. Mol. Biol. Cell 15(5): 2189–2204.

10) Abeliovich, H., Zhang, C., Dunn, W.A. Jr., Shokat, KM., and D.J. Klionsky (2003). Chemical genetic analysis of Apg1 reveals a non–kinase role in the induction of autophagy. Mol. Biol. Cell 14(2):477–490.

11) Abeliovich, H. and D.J. Klionsky (2001). Autophagy in yeast: Mechanistic insights and physiological function Microbiol. Mol. Biol. Rev. 65(3):463–79.

12) Wang, C.–W., Kim, J., Huang, W.–P., Abeliovich, H., Stromhaug, P.E., and D.J. Klionsky (2001). Apg2 is a novel protein required for the cytoplasm to vacuole targeting, autophagy, and pexophagy pathways. J. Biol. Chem. 276(32):30442–51.

13) Abeliovich, H., Dunn, W.A. Jr., Kim, J., Klionsky, D.J. (2000). Dissection of autophagosome biogenesis into distinct nucleation and expansion steps. J. Cell Biol. 151(5): 1025–1033.

14) Abeliovich, H., Darsow, T., Emr, S.D. (1999). Cytoplasm–to–vacuole trafficking of aminopeptidase I requires a t–SNARE/Sec1p complex composed of Tlg2p and Vps45p. EMBO J. 18(21): 6005–6016.

15) Sacher, M., Jiang, Y., Barrowman, J., Scarpa, A., Burston, J., Zhang, L., Schieltz D., Yates, J.R. III, Abeliovich, H., Ferro–Novick S. (1998). TRAPP, a highly conserved novel complex on the cis–Golgi that mediates vesicle docking and fusion. EMBO J. 17(9):2494–503.

16) Abeliovich, H., Grote, E., Novick, P., Ferro–Novick, S. (1998). Tlg2p, a yeast syntaxin homolog that resides on the Golgi and endocytic structures. J. Biol. Chem. 273(19):11719–27.

17) Tzfati, Y., Abeliovich, H., Avrahami, D., Shlomai, J. (1995). Universal minicircle sequence binding protein, a CCHC–type zinc finger protein that binds the universal minicircle sequence of trypanosomatids. Purification and characterization. J. Biol. Chem. 270(36):21339–45.

18) Abeliovich, H., Shlomai, J. (1995). Reversible oxidative aggregation obstructs specific proteolytic cleavage of glutathione S–transferase fusion proteins. Anal. Biochem. 228(2):351–4.

19) Abeliovich, H., Tzfati, Y., Shlomai, J. (1993). A trypanosomal CCHC–type zinc finger protein which binds the conserved universal sequence of kinetoplast DNA minicircles: isolation and analysis of the complete cDNA from Crithidia fasciculata. Mol.Cell Biol. 13(12):7766–73.

20) Tzfati, Y., Abeliovich, H., Kapeller, I., Shlomai J (1992). A single–stranded DNA–binding protein from Crithidia fasciculata recognizes the nucleotide sequence at the origin of replication of kinetoplast DNA minicircles. Proc. Natl .Acad. Sci. U S A. 89(15):6891–5.