huji Institute of Biochemistry, Food Science and Nutrition

Robert H. Smith Faculty of Agriculture, Food and Environment,
The Hebrew University of Jerusalem

Professor Oren Tirosh

Professor Oren Tirosh

List of Publications

  • Shilo S., Aharoni-Simon M., Tirosh O. (2005) Selenium attenuates expression of MnSOD and uncoupling protein 2 in j774.2 macrophages: molecular mechanism for its cell-death and anti-inflammatory activity, Antioxid. Redox. Signal., 7(1&2): 276-286. 5.48;12/92; 5
  • Aronis A., Madar Z., Tirosh O. (2005) Mechanism underlying oxidative stress-mediated lipotoxicity: exposure of J774.2 macrophages to triacylglycerols facilitates mitochondrial ROS production and cellular necrosis, Free Rad. Biol. Med., 38(9):1221-1230. 4.81;18/82; 31
  • Zubare-Samuelov M., Shaul M.E. , Peri I, Aliluiko A, Tirosh O, Naim M. (2005) Inhibition of signal-termination-related kinases by membrane-permeant bitter and sweet tastants: potential role in taste-signal termination, Am. J Physiol. Cell Physiol., 289(2):C483-492. 4.2; 9/78; 4
  • Ilan E., Tirosh O., Madar Z. (2005) Triacylglycerol-mediated oxidative stress inhibits nitric oxide production in rat isolated hepatocytes, J. Nutr., 135(9):2090-2095. 3.77; 7/56; 5
  • Tirosh O ., Pardo M., Schwartz B . , Miskin R. (2005) Long-lived alphaMUPA transgenic mice show reduced SOD2 expression, enhanced apoptosis and reduced susceptibility to the carcinogen dimethylhydrazine, Mech. Ageing Dev. 126(12): 1262-1273, 4.3; 5/31; 8
  • Dasgupta J., Subbaram S., Connor K.M., Tirosh O., Melendez J.A. (2006) Manganese Superoxide Dismutase protects from TNF-α induced apoptosis by increasing the steady state production of H2O2, Antioxid. Redox. Signal. 8(7-8): 1295-1305, 7.58; 5/105; 22
  • Aharoni-Simon M., Reifen R., Tirosh O., (2006) ROS-Production-Mediated Activation of AP-1 but Not NFkB Inhibits Glutamate-Induced HT4 Neuronal Cell Death, Antioxid. Redox. Signal. 8(7-8): 1339-1349, 7.58;5/105;1
  • Abovich-gilad L., Tirosh O., Schwartz B., (2006) Phytoestrogens regulate transcription and translation of vitamin D receptor in colon cancer cells, J. Endocrinol., 191(2): 387-398. 2.8;48/105; 12
  • Pardo M., Melendez J.A., Tirosh O. (2006) MnSOD Inactivation during Fas (CD95)-mediated apoptosis in Jurkat T cells, Free Rad. Biol. Med., 41(12): 1795-1806. 6.081;12/105; 8
  • Shilo S., Pardo M., Aharoni-Simon M. , Gliebter S., Tirosh O. (2008) Selenium supplementation increases liver MnSOD expression: molecular mechanism for hepato-protection, J Inorg Biochem., 102(1):110-8. 3.25;9/44; 8
  • Tirosh O., Levy E. , Reifen R. (2007) High-selenium diet protects
    against TNBS-induced acute inflammation, mitochondrial dysfunction and secondary necrosis in rat colon, Nutrition, 23(11-12):878-86. 2.6;23/66; 11
  • Aronis A., Madar Z., Tirosh O. (2008) Lipotoxic effects of triacylglycerols in J774.2 macrophages, Nutrition. 24(2):167-76. 2.6;23/66; 9
  • Budick-harmelin N., Dudas J., Demuth J., Madar Z., Ramadori G. Tirosh O. (2008) triglycerides potentiate the inflammatory response in rat kupffer cells, Antioxid. Redox. Signal., 10(12):2009-22. 7.58;5/105;7
  • Tirosh O. , Ilan E. , Anavi S., Ramadori G., Madar Z. (2009) Nutritional lipids-induced oxidative stress leads to mitochondrial dysfunction followed by necrotic death in FaO hepatocytes, Nutrition, 25(2):200-8. 2.6;23/66, 2
  • Pardo M., Budick-harmelin N., Tirosh B., Tirosh O. (2008) Antioxidant defense in hepatic ischemia-reperfusion injury is regulated by damage-associated molecular pattern signal molecules, Free Rad. Biol. Med., 45(8):1073-83. 6.081;12/105;6
  • Tirosh O. , Ilan E. , Budick-harmelin N. , Ramadori G. , Madar Z. (2009) Down regulation of eNOS in a nutritional model of fatty liver, e-SPEN. 4(2);e101-e104. (1 citation)
  • Pardo M., Tirosh O., (2009) Protective signaling effect of Manganese superoxide dismutase in hypoxia-reoxygenation of hepatocytes, Free Radical Research, 43(12):1225-39. 2.25;176/283,3
  • Aronis A., Aharoni-Simon M., Madar Z., Tirosh O. (2009) Triacylglycerol-induced impairment in mitochondrial biogenesis and function in J774.2 and mouse peritoneal macrophage foam cells. Arch. Biochem. Biophys. 492(1-2):74-81. 2.63, 30/70, 3
  • Tirosh O. , Artan A., Aharoni-Simon M. , Ramadori, G. , Madar Z. (2010) Impaired liver glucose production in a murine model of steatosis and endotoxemia: protection by inducible nitric oxide synthase. Antioxid. Redox. Signal., 13(1):13-26. 7.58; 5/105; (appears on journal cover)
  • Anavi S. , Ilan E. , Tirosh O. , Madar Z. (2010) Infusion of a lipid emulsion modulates AMPK and related proteins in rat liver, muscle and adipose tissues. Obesity, 18(6):1108-15, 2.76,16/59, 2
  • Aharoni-Simon M., Hann-Obercyge M. , Pen S. ,Madar Z. , Tirosh O. (2011) Fatty Liver is Associated with Impaired Activity of PPAR gamma-Coactivator 1alpha; (PGC1alpha) and Mitochondrial Biogenesis in Mice, Laboratory Investigation, 91(7):1018-28, 4.6, 16/93


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