Arie Altman, Ph.D
Tel: 972-8-9489477; fax: 972-8-9489899; email:
altman@agri.huji.ac.il
Born in Israel, July 8, 1937; M.Sc. 1964, Ph.D. 1970,
The Hebrew University of Jerusalem; Lecturer 1970; Senior
Lecturer 1977; Associate Professor 1982; Professor 1989. Emeritus
Married
to Judith, a daughter (Orly) and a son (Ron).
Other professional activities:
Hebrew University and local: Founder and President,
Israeli Society of Plant Propagation. (1979-1981); Chairman,
Teaching Board, The Faculty of Agriculture (1986-1989); Director,
The Otto Warburg Center of Biotechnology in Agriculture (1992
1998); Member, Standing Committee and Academic Policy Committee,
HU (1997-2000); Member, National Committee for Biotechnology and
Chairman, National Sub-Committee for Plant Genomics (2000- );
Founding Chairperson, Institute of Plant Sciences and Genetics in
Agriculture (1999-2005).
International : Chairman, Organizing Committee,
International Symposium "Frontiers of Biotechnology in
Agriculture (1991); Chairman, In Vitro Culture Working Group,
International Society of Horticultural Science (1994-1997);
Chairman, Organizing Committee, Second International Symposium on
the Biology of Root Formation, Jerusalem (1996); President,
International Association of Plant Tissue
Culture&Biotechnology (IAPTC&B) (1994-1998); Executive
Committee, IAPTC&B (1998-2002).
Sabbatical leaves/Invited Professor: Dept. of Biology,
Yale University, New Haven, USA; Dept. of Biochemistry, Roche
Institute of Molecular Biology, USA; Scripps Research Institute,
La Jolla, USA; Dept. of Botany, University of Natal, South
Africa; INRA, Versailles, France; Dept. of Plant Morphogenesis,
University of Paris VI, France; Dept. of Plant Ecology and
Physiology, Amsterdam Free University, The Netherlands.
Editorial Boards: Plant Physiology (1987-1991); Plant
Tissue Culture and Biotechnology (1994-1998); Annual Review of
Plant Biotechnology and Applied Genetics (1997-2005); Israel
Journal of Plant Sciences (1995-2004); In Vitro Cellular &
Developmental Biology-Plant; Electronic Journal of Biotechnology;
Editor: Plant Cell Reports.
RESEARCH FIELDS AND INTERESTS
Molecular regulation of plant response to drought and salinity:
The molecular basis of abiotic stress tolerance in plants,
especially drought, salinity and extreme temperatures, is
rather limited. In view the worldwide devastating problems of
salinization and desertification, both in relation to food
production and to environment degradation, we are involved in
several research projects directed at elucidating some of the
molecular regulation of tolerance to abiotic stress, especially
drought and salinity. Poplar trees, Arabidopsis, tomato
and the model halophyte Thellungiella halophila are the
major plants studied. Plant adaptation
to environmental stresses is controlled by cascades of
molecular networks which activate stress-responsive mechanisms
to re-establish homeostasis and protect damaged proteins and
membranes. Stress-associated proteins and metabolites are two
major key regulators of adaptation to abiotic stress which are
intensively studied in our laboratory.
While the study of stress proteins and proteomics has already
received considerable attention, our understanding of the
contribution of the metabolome to stress tolerance is just
emerging. Below is a summary of our recent findings on two
unique stress-associated related proteins, Populus SP1
and Arabidopsis AtSP, and on stress-associated
metabolite profiling. The research is carried out with 4
different plant species (Populus euphratica, tomato,
Arabidopsis thaliana and Thellungiella
halophila/salsuginea) and under different salt
stress regimes.
Recently, we characterized a new exceptionally stable,
homo-oligomeric protein (SP1), having a potent chaperone-like
activity.
The SP1 represents a novel class of proteins with a dual role:
both in plant stress tolerance, and as novel nanobiomolecule
for biotechnological applications. SP1 protein was isolated and
characterized initially in Populus tremula L. The
sp1 gene encodes a 12.4 kDa novel boiling-stable
hydrophilic protein (SP1). Northern blot analysis revealed that
sp-1 encodes a small mRNA (about 0.6 kb), which is
constitutively expressed in plants, but
its accumulation is stimulated by stress conditions. In planta,
SP1 is found at several sizes, and detailed protein analysis
established that SP1 is a homo-oligomeric protein, existing in
aspen plants as a complex composed of several 12.4 kDa
subunits. Recombinant SP1 retained similar characteristics when
expressed in E. coli.Two
genomic sp1 related sequences that are highly homologous
were isolated, as well as the corresponding promoters.
The SP1 is exceptionally resistant to many harsh conditions,
which normally degrade proteins. SP-1 transcripts were
over-expressed in transgenic aspen, showing an increased
tolerance to high levels of NaCl. In vitro, SP-1 is highly
potent in protecting the activity of several diagnostic and
industrial enzymes from heat-inactivation, and can serve as a
nanomolecule for drug delivery. Proteins with similar
characteristics have been found in several other plant species
and homologous genes and proteins were found in Populus
euphratica, an extremely salt tolerant species, as well as
in Arabidopsis. We established that P. euphratica
trees can maintain cellular homeostasis and show unique
adaptation and tolerance to salt stress by the activation of
different unique mechanisms. The following characteristics seem
especially important: (1) the ability to tolerate high levels
of Na+, Cl- and Ca2+ in the
leaves, (2) a capacity to up-regulate the synthesis of
different inorganic and organic acids (such as phosphoric acid
and quinic acid), thus maintaining normal cell functioning, (3)
maintainance of leaf cell turgor by the synthesis of high
concentrations of mono and oligosaccharides (osmolytes), (4)
P. euphratica trees developed, during their evolutionary
adaptation to salt, a higher basal level of SP1 (relative to
P. tremula, a salt sensitive species), and (5) SP1 is
sumoylated upon salt stress, and is consequently translocated
from the cytosol to the plasmalemma (possibly contributing to
membrane stabilization and functioning) and to the nucleus
(possibly associated to the chromatin).
Following cloning of Atsp, the Arabidopsis SP1
homolog, we showed its thermostability and resistance to
protease, as well as its chaperon-like activity in vitro. To
better understand the biologic functions of Atsp, we use
a strategy of reverse genetics, transforming A. thaliana
plants with an RNAi vector resulting in several independent
knock-out lines showing no apparent AtSP protein accumulation.
Preliminary results show that growth of the RNAi line is
considerably reduced, and the under-expressing line is more
sensitive to salt stress. In addition, we found that expression
of the bacterial beta gene in tomato results in glycine betaine
in the transgenic tomato (unlike the wild type which does not
accumulate glycine betaine) and in increased salt stress
tolerance. This was accompanied by changes in metabolite
profiles and in the expression of HSP70. We propose that
overproduced glycine betaine in tomato acts as an
osmoprotectant to stabilize functional and/or structural
proteins and in signaling changes in several metabolites.
An integrated physiological and
metabolic characterization of salt cress (Thellungiella
halophila) adaptation to high salinity stress was carried
out, and compared with that of A. thaliana. We
found that The significant a salt stress tolerance of
Thellungiella is achieved by a combination of low levels of Na+ and Cl-
uptake by the roots, and by the fact that even those levels of
Na+ and Cl- that accumulate in the leaves
have no effect onplant growth and protein levels, being probably sequestered in the
vacuole. Significantly high basal levels of several metabolites
were found in Thellungiella, relative to the low levels
found in Arabidopsis.
(click on picture for larger version)
Forestry biotechnology:
Forests are very important both to the world economy, having a
wide range of commercial uses, and for maintaining and
preserving our ecosystem. To lower the pressure on existing
forests, an intensive effort is needed to include trees in the
modern era of biotechnology. Although molecular breeding is
routine in agriculture, forest-tree species have been left far
behind. The potential of biotechnology for accelerating
forest-tree-breeding programs can be realized at several
levels, including clonal propagation of superior genotypes, and
direct introduction of specific traits via genetic engineering.
These two aspects are being studied in our laboratory. We
developed efficient procedures for micropropagation of
Populus species, especially P. tremula and P.
euphratica, using shoot bud regeneration form stem and root
explants, from callus, and in liquid cultures of roots. A large
number of buds were produced from mature cotyledon explants of
Pinus halepensis, and plants were recovered. Similar
procedures were used for cloning of Fagus sylvatica.
Highly efficient transformation rates, using A.
rhizogenes and A. tumefaciens, were achieved in
P. tremula. Using these procedures and several A.
rhizogenes rol genes, we have recovered transgenic plants
with improved growth rate in vitro, as well as improved rooting
characteristics and stem:root production index. Tolerance to
drought and salinity stress is being investigated in Populus
tremula, Populus euphratica and Pinus
halepensis (see above).
Plant tissue culture and propagation:
Clonal propagation of agricultural plants is becoming
increasingly important, not only (as it was traditionally) in
ornamental plants, but also in several other crops, including
vegetables and trees. Our laboratory has been and is involved
in studying hormonal and environmental control of
embryogenesis, organogenesis and tissue development in culture.
This resulted in the application of vitro procedures for rapid
clonal propagation (as well as for physiological and molecular
studies) of poplar species, Citrus, pine and Fagus,
celery, Allium and several other species.
REPRESENTATIVE PUBLICATIONS
Vinocur, B. and A. Altman (2005).
Recent advances in engineering plant tolerance to abiotic
stress: achievements and limitations. Curr. Opinion
Biotecnology 16: 1-10.
Mikael Brosché, Basia Vinocur, Edward R
Alatalo, Airi Lamminmäki, Thomas Teichmann, Eric A Ottow,
Dimitar Djilianov, Dany Afif, Marie-Béatrice
Bogeat-Triboulot, Arie Altman, Andrea Polle, Erwin
Dreyer, Stephen Rudd, Lars Paulin, Petri Auvinen and Jaakko
Kangasjärvi
(2005). Gene expression metabolite profiling of Populus
euphratica growing in the Negev desert. Genome
Biology 2005,
6
Or Dgany, Ana Gonzalez , Oshrat Sofer, Wangxia
Wang, Gennady Zolotnitsky, Amnon Wolf , Yuval Shoham, Arie
Altman, Sharon G. Wolf, Oded Shoseyov and Orna Almog
(2004). Structural Basis of the Thermostability of SP1, a Novel
Plant (Populus tremula) Boiling Stable Protein. Journal
of Biological Chemistry 279: 51516 – 51523.
Wang, W.,B. Vinocur, O.
Shoseyov and A.
Altman(2004). The role of plant heat-shock proteins/molecular
chaperones in the abiotic
stress response. Trends in Plant
Science 9: 244-252.
Altman, A. (2003).From plant tissue
culture to biotechnology: scientific revolutions, abiotic
stress tolerance, and forestry. from plant tissue culture to
biotechnology: scientific revolutions, abiotic stress
tolerance, and forestry. In Vitro Cell. Dev. Biol.—Plant
39:75–84.
Wang, W.,B. Vinocur and
A. Altman (2003). Plant responses to drought, salinity
and extreme temperatures: towards genetic engineering for
stress tolerance. Planta 218: 1–14.
Ziv, M. and A. Altman (2003).Plant
Tissue Culture: General Principles. Encyclopedia of Applied
Plant Sciences, Elsevier Science Ltd.
Chen S , Li, J., Wang, S., Fritz, E.,
Huettermann, A. and Altman, A. (2003). Effects of NaCl
on shoot growth, transpiration, ion compartmentation and
transport in regenerated plants of Populus euphratica and P.
Canad. J. Forestry Res. 33: 967-975.
Wang, W.G., D. Pelah, T. Alergand, O.
Shoseyov and A.
Altman(2002). cDNA cloning, expression
and characterization of SP1, an oligomeric water-stress
responsive boiling stable protein. Plant Physiology130:
865-875.
Wang, W.G., D. Pelah, T. Alegrand, O.
Shoseyov and A.
Altman(2001)."Boiling and/or
detergent stable, and/or protease resistant, chaperone-like
oligomeric proteins, polynucleotides encoding the same, and
their uses" Patent application).
Chen, S., J. Li, S. Wang, A.
Huttermann and A.
Altman. (2001). Salt, nutrient uptake and transport, and ABA of
Populus euphratica hybrid in response to increasing soil NaCl.
Trees 15: 186-194.
Altman, A.and
B. Loberant (2000). Micropropagation of plants: principles and
practices. In: R. Spier, ed., Encyclopedia of Cell Technology,
Vol. 1: 916-929. John Wiley & Sons, Inc., New York
Tzfira, T., A. Vainstein and A. Altman
(1999). rol-gene expression in transgenic aspen (Populus
tremula) plants results in accelerated growth and improved stem
production index. Trees 14: 49-54.
Altman, A. (1999). Plant biotechnology in the 21st century: the
challenges ahead. Electronic J. Biotechnology
Altman, A. (1999). The plant and agricultural biotechnology
revolution: where do we go from here? In: A. Altman, M. Ziv and
S. Izhar, eds., Plant Biotechnology and In Vitro Biology in the
21st Century. Kluwer Academic Publishers, Dordrecht, The
Netherlands, pp. 1-7.
Altman, A. ed. (1998). Agricultural Biotechnology.
Marcel Dekker, Inc., New York, ISBN:
0-8247-9439-7. 770 pp.
Tzfira, T., A. Zuker and A. Altman
(1998). Forest tree biotechnology: genetic transformation and
application to future forests. Trends in Biotechnology 16:
439-446.
Arie Altman, Publications 1997-2003
Pelah, D., W. Wang, A. Altman, O.
Shoseyov and D. Bartels (1997). Differential accumulation of
water-stress related proteins, sucrose synthase and soluble
sugars in Populus genotypes which differ in their water-stress
response. Physiol. Plant. 99: 153-159.
Pelah, D., O. Shoseyov, A. Altman and
D. Bartels (1997). Water-stress response in aspen (Populus
tremula): differential accumulation of dehydrin, sucrose
synthase, GAPDH homologues
and soluble sugars. J. Plant Physiol.
151: 96-100.
Tzfira, T., C. S. Jensen, A.
Vainstein and A. Altman (1997). Transformation and
regeneration of transgenic aspen plants via shoot formation
from stem explants. Physiol. Plant. 99: 554-561.
Schwartz, M., A. Altman, Y.
Cohen and T. Arzee (1997). Inhibition
of polyamine biosynthesis by L-canavanine and its effect on
meristematic activity, growth, and development of Zea mays
roots. Israel J. Plant Sci. 45: 23-30.
Pelah, D., M.Dekel, N. Rosenberg, N. Navot,
A. Altman and H. Czosnek (1997). Tomato yellow leaf curl
virus (TYLCV) DNA replication in protoplasts derived from
tomato genotypes, sensitive, tolerant and resistant to the
virus. Plant Tissue Culture and Biotechnology 3: 97-106.
Tzfira, T.,C. S. Jensen, W-X.
Wang, A. Zuker, B. Vinocur, A.
Altman and A. Vainstein (1997). Transgenic Populus tremula: a
step-by-step protocol for its
Agrobacterium-mediated transformation.
Plant Molec. Reporter 15: 219-235.
Chen, S-L., S-S. Wang, A. Altman and
A. Huttermann (1997). Genotypic variation in drought tolerance
of poplar in relation to abscisic acid. Tree Physiol. 17:
797-803.
Ma, H-C, L. Fung, S-S.
Wang, A. Altman and A. Huttermann
(1997). Photosynthetic response of Populus euphratica to salt
stress. Forest Ecology and Management 93: 55-61.
Tzfira, T.,C. S. Jensen, A.
Vainstein and A. Altman (1997). Aspen transformation procedures:
oncogenic Agrobacterium rhizogenes versus disarmed
Agrobacterium tumefaciens. In A. Altman and M. Ziv, eds,
Horticultural Biotechnology: In Vitro Culture and Breeding,
Acta Horticulturae 447, pp. 295-300.
Jensen, C.S., T. Tzfira, A. Vainstein and
A. Altman (1997). Direct regeneration and selection of
Populus tremula L. transgenic shoots from Agrobacterium
tumefaciens-transformed stem explants. In: A. Altman and Y.
Waisel, eds. The Biology of Root Formation and Development,
Plenum Press, pp. 209-211.
Pelah, D., O. Shoseyov and A. Altman
(1997). Drought tolerance: a molecular perspective. In A.
Altman and M. Ziv, eds, Horticultural Biotechnology: In Vitro
Culture and Breeding, Acta Horticulturae 447, pp.
439-445.
Wang, W-X., D. Pelah, A. Altman and O.
Shoseyov (1997). Clonal differences in the expression of a
water stress related protein (BspA) in Populus spp. In A.
Altman and M. Ziv, eds, Horticultural Biotechnology: In Vitro
Culture and Breeding, Acta Horticulturae 447, pp.
467-468.
Altman, A.
and M. Ziv (1997). Horticulture biotechnology: a historical
perspective and future prospects. In A. Altman and M. Ziv, eds,
Horticultural Biotechnology: In Vitro Culture and Breeding,
Acta Horticulturae 447, pp. 31-35.
Carmi, T., M. Ziv and A. Altman
(1997). Bud regeneration, growth and proliferation of aspen
(Populus tremula) roots in liquid cultures. In A. Altman and M.
Ziv, eds, Horticultural Biotechnology: In Vitro Culture and
Breeding, Acta Horticulturae 447, pp. 669-670.
Bockish, T., Y. Saranga and A. Altman
(1997). Garlic micropropagation by somatic embryogenesis. In A.
Altman and M. Ziv, eds, Horticultural Biotechnology: In Vitro
Culture and Breeding, Acta Horticulturae 447, pp.
241-242.
Tzfira, T., A. Vainstein and A. Altman
(1997). Improved rooting ability and root system performance in
transgenic aspen plants. In: A. Altman and Y. Waisel, eds. The
Biology of Root Formation and Development, Plenum Press, pp.
181-186.
Vinocur, B., T. Tzfira, M. Ziv A. Vainstein
and A. Altman (1997). Bud regeneration and growth from
transgenic and non transgenic aspen (Populus tremula) root
explants. In: A. Altman and Y. Waisel, eds. The Biology of Root
Formation and Development, Plenum Press, pp. 217-219.
Meiri, H. and A. Altman (1998).
Agriculture and agricultural biotechnology: Development trends
towards the 21st century. In: A. Altman, ed. (1998).
Agricultural Biotechnology. Marcel Dekker, Inc., New York, pp.
1-17.
Altman, A. and B. Loberant (1998). Micropropagation: Clonal plant propagation in
vitro. In: A. Altman, ed. (1998).
Agricultural Biotechnology. Marcel Dekker, Inc., New York, pp.
19-42.
Tzfira, T., A. Zuker and A. Altman
(1998). Forest tree biotechnology: genetic transformation and
application to future forests. Trends in Biotechnology 16:
439-446.
Tzfira, T., B. Vinocur, A. Altman and
A. Vainstein (1998). rol-transgenic Populus tremula: root
development, root-borne bud regeneration and in vitro
propagation coefficient. Trees 12: 464-471.
Fung, L.E., S.S. Wang, A. Altman and
A. Huttermann (1998). Effect of NaCl on growth, photosynthesis,
ion and water relations of four poplar genotypes. Forest
Ecology and Management 107: 135-146.
Tzfira, T., A. Vainstein and A. Altman
(1999). rol-gene expression in transgenic aspen (Populus
tremula) plants results in accelerated growth and improved stem
production index. Trees 14:
49-54.
Altman, A.
(1999). Le peuplier, le stress et
la transgenese. Biofutur 188:
36-39.
Altman, A. (1999). The plant and agricultural biotechnology
revolution: where do we go from here? In: A. Altman, M. Ziv and
S. Izhar, eds., Plant Biotechnology and In Vitro Biology in the
21st Century. Kluwer Academic Publishers, Dordrecht, The
Netherlands, pp. 1-7.
Ovadis, M., Chernin, L., Tzfira, T., Canaan,
V., Aharoni, A., Sakar, D., Altman,
A., Vainstein, A. (1999). Transformation of tobacco and
aspen plants with the ITA locus of an INCQ plasmid confers
resistance to Agrobacterium tumefaciens infection. In: Altman
A., Ziv M. and Izhar, S. (eds.). Plant biotechnology and in
vitro biology in the 21st century. Kluwer Academic Publishers,
Dordrecht, The Netherlands, pp: 533-536.
Shani, Z., Dekel, M., Tsabary, G., Jensen,
Ch., Tzfira, T., Goren, R., Altman, A and Shoseyov, O.
(1999).Expression of Arabidopsis thaliana endo-1,4-(-glucanase
(cel1) in transgenic poplar plants. In: Altman A., Ziv M. and
Izhar, S. (eds.). Plant biotechnology and in vitro biology in
the 21st century. Kluwer Academic Publishers, Dordrecht, The
Netherlands, pp: 209-212.
Shani, Z., Shpigel, E., Roiz, L., Goren, R.,
Vinocur, B., Tzfira, T., Altman, A and Shoseyov, O.
(1999). Cellulose binding domain increases cellulose synthase
activity in Acetobacter xylinum, and biomass in transgenic
plants. In: Altman A., Ziv M. and Izhar, S. (eds.). Plant
biotechnology and in vitro biology in the 21st century. Kluwer
Academic Publishers, Dordrecht, The Netherlands, pp:
213-218.
Tzfira, T., Ya’ari, A., Yarnitzky, O., Riov,
J. and Altman, A. (1999). In vitro propagation of Aleppo
pine (Pinus halepensis Mill.). In: Altman A., Ziv M. and Izhar,
S. (eds.). Plant biotechnology and in vitro biology in the 21st
century. Kluwer Academic Publishers, Dordrecht, The
Netherlands, pp: 89-92.
Wang, W.X., Tzfira, T.,Levin, N., Shoseyov, O
and Altman, A. (1999). Plant
tolerance to water and salt stress: The expression pattern of a
water stress responsive protein (BspA) in transgenic aspen
plants. In: Altman A., Ziv M. and Izhar, S. (eds.). Plant
biotechnology and in vitro biology in the 21st century. Kluwer
Academic Publishers, Dordrecht, The Netherlands, pp: 561-565.
Shani, Z., M. Dekel, C.S. Jensen, T. Tzfira,
R. Goren, A. Altman, O. Shoseyov (1999). Arabidopsis
thaliana endo-1,4,-b-glucanase (cel1) promoter mediates uidA
expression in elongating tissues of aspen (Populus tremula). J.
Plant Physiol. 156: 118-120.
Altman, A. (1999). Plant biotechnology in the 21st century: the
challenges ahead. Electronic J. Biotechnology
Tzfira, T., W. Wang and A. Altman (2000).
Genetic transformation of Populus towards improving plant
performance and drought tolerance. In: S.M. Jain and S.C.
Minocha, eds., Molecular Biology of Woody Plants. Vol.2:
135-160. Kluwer Academic Publishers.
Alian, A., A. Altman and B. Heuer
(2000). Genotypic differences in salinity and water stress
tolerance of fresh market tomato cultivars. Plant Sci. 152:
58-65.
Altman, A. and B. Loberant (2000). Micropropagation of plants:
principles and practices. In: R. Spier, ed., Encyclopedia of
Cell Technology, Vol. 1: 916-929. John Wiley & Sons, Inc.,
New York
Altman, A.,
T. Tzfira, W. Wang, B. Vinocur, G. Hazan and A. Vainstein
(2000). Clonal stability, seasonal periodicity and transgenes:
the lesson from long-term micropropagation of transgenic and
non-transformed Populus tremula L. Plants. In: A. C.
Cassels et al., eds, Int. Symp. on Methods and Markers for
Quality Assurance in Micropropagation, Acta Horticulturae 530:
429-436.
Vinocur, B., T. Carmi, A. Altman and
M. Ziv (2000). Enhanced bud regeneration in aspen (Populus
tremula L.) roots cultured in liquid medium. Plant Cell Reports
19: 1146-1154.
Wang, W.X., B. Vinocur, O. Shoseyov and A. Altman (2001).
Biotechnology of plant osmotic
stress tolerance: physiological and molecular considerations. In: S. Sorvari et al., eds., Int. Symp. on In Vitro Culture and Horticultural Breeding,
Acta Horticulturae 560: 285-292.
S. Chen, J. Li, S. Wang, A. Huttermann and A. Altman. (2001). Salt, nutrient uptake and
transport, and ABA of Populus euphratica hybrid in response to
increasing soil NaCl. Trees 15: 186-194.
Wang, W.G., D. Pelah, T. Alegrand, O. Shoseyov and A. Altman (2001). "Boiling and/or
detergent stable, and/or protease resistant, chaperone-like oligomeric proteins,
polynucleotides encoding the same, and their uses" (Patent application).
Wang, W.G., D. Pelah, T. Alergand, O. Shoseyov and A. Altman (2002). cDNA cloning,
expression and characterization of SP1, an oligomeric water-stress responsive boiling stable protein. Plant Physiology130: 865-875.
Altman, A. (2003). From plant tissue culture to biotechnology: scientific revolutions,
abiotic stress tolerance, and forestry. from plant tissue culture to biotechnology: scientific revolutions, abiotic stress tolerance, and forestry.
In Vitro Cell. Dev. Biol.- Plant 39:75-84
Wang, W.G., T. Barak, B. Vinocur, O. Shoseyov and A. Altman (2003). Abiotic resistance
and
chaperones: possible physiological role of SP1, a stable and stabilizing protein from Populus. In: Plant Biotechnology 2002 and Beyond (ed. I. K. Vasil), Kluwer Aca
demic Publishers, Dordrecht, Boston, London. pp. 439-443.
Chen S , Li, J., Wang, S., Fritz, E., Huettermann, A. and Altman, A. (2003).Effects of
NaCl
on shoot growth, transpiration,
ion compartmentation and transport in
regenerated plants of Populus euphratica and P. tomentosa. Canadian J. of Forest Res.
33: 967-975
Wang, W., O. Dgany, O. Dym, A. Altman, O. Shoseyov and O. Almog (2003). Crystallization
and
preliminary X ray crystallographic analysis of SP1, a novel chaperone-like protein. Acta Cryst. D59: 512-514.
Ziv, M. and A. Altman (2003). Plant Tissue Culture: General Principles. Encyclopedia of
Applied Plant Sciences, Elsevier Science Ltd.
Wang, W., B. Vinocur and A. Altman (2003). Plant responses to drought, salinity and
extreme
temperatures: towards genetic engineering for stress tolerance. Planta 218: 1-14.
Wang, W., B. Vinocur, O. Shoseyov and A. Altman (2004). The role of plant heat-shock
proteins/molecular chaperones in the abiotic stress response. Trends in Plant Science 9: 244-252.
Or Dgany, Ana Gonzalez , Oshrat Sofer, Wangxia Wang, Gennady Zolotnitsky, Amnon Wolf ,
Yuval Shoham, Arie Altman, Sharon G. Wolf, Oded Shoseyov and Orna Almog (2004).
Structural Basis of the Thermostability of SP1, a Novel Plant (Populus tremula) Boiling
Stable Protein. Journal of Biological Chemistry 279: 51516-51523.
Pelah, D., I. Marton, W. Wang, O. Shoseyov, A. Altman and E. Cohen (2004). Accumulation
and
protection activity of protease-resistant heat-stable proteins in Haematococcus pluvialis during high light and nitrogen starvation. Jour. Applied Phycology 16: 15
3-155.
Mizrachy, L., D. Dabush, Y. Levy, R. Aloni and A. Altman (2004). Cloning and
characterization of the tomato karyopherin-1 gene promoter. Devlop. Growth. Differ.
46: 515-522.
Vinocur, B. and A. Altman (2005). Recent advances in engineering plant tolerance to
abiotic stress: achievements and limitations. Curr. Opinion Biotecnology 16: 1-10.
Mikael Brosché, Basia Vinocur, Edward R Alatalo, Airi Lamminmäki, Thomas Teichmann,
Eric A Ottow, Dimitar Djilianov, Dany Afif,
Marie-Béatrice Bogeat-Triboulot, Arie Altman, Andrea Polle, Erwin Dreyer, Stephen
Rudd, Lars Paulin, Petri Auvinen and Jaakko
Kangasjärvi (2005). Gene expression metabolite profiling of Populus euphratica growing
in the Negev desert. Genome Biology 2005, 6
Andrea Polle, Arie Altman and Xiangning Jiang (2006). Towards Genetic Engineering for
Drought Tolerance in Trees. In:M.Fladung and D.Ewald (Eds.) Tree Transgenesis: Recent Developments. Springer-Verlag Berlin Heidelberg.
Update: July 2006
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