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Tamar Friedlander Tamar Friedlander

Tel: 972-8-9489684   
Fax: 972-8-948-9322

E-mail: tamar.friedlander@mail.huji.ac.il

 

 

 

 

 

 

Research Interests

My lab is computational - theoretical. We use a variety of methods including evolutionary and biophysical modeling, computer simulations and bioinformatics to research fundamental biological questions.

We study self-incompatibility in plant fertilization and general principles underlying the evolution and organization of gene regulatory networks. “Self-incompatibility” is a general name for molecular mechanisms, plants have developed to avoid self-fertilization, which might lead to the spread of deleterious mutations. Research of this system addresses fundamental evolutionary questions and has practical implications on crop fertilization.

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We are hiring!

Msc/ PhD/ post-doc positions are available. For details contact me at tamar.friedlander@mail.huji.ac.il

Selected Publications

  • T. Friedlander*, R. Prizak*, N. Barton and G. Tkacik, “Evolution of new regulatory functions on biophysically realistic fitness landscapes”, (* - equal contribution), arXiv: 1610:02864, Nature Communications, accepted, 2017.
  • T. Friedlander, R. Prizak, C. Guet. N. Barton and G. Tkačik, “Intrinsic limits to gene regulation by global crosstalk”, Nature Communications, 7(12307), Aug. 2016, doi:10.1038/ncomms12307; (arXiv:1506.06925).
  • T. Friedlander and N. Brenner, "Adaptive Response by State-Dependent Inactivation", Proceedings of the National Academy of Sciences, 106(52):22558-22563, December 29, 2009; published online December 15, 2009, doi:10.1073/pnas.0902146106.

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