FRIDMAN, EYAL
Senior Lecturer
Born: Moshav Amatzia
Ph.D. Hebrew University
The Hebrew University of Jerusalem
Faculty of Agricultural, Food Quality and Environmental Sciences
Robert H. Smith Institute of Plant Sciences and Genetics
Rehovot 76100 Israel
Phone: +972-8-9489513
Fax: +972-8-9468265
e-mail: fridmane@agri.huji.ac.il
Radiation, adaptation and hybridization:
Consequences and applications
Radiation and adaptation to different environments involve the change in the
genetic make-up as a result of both natural selection and stochastic processes.
Hybridization of these genomes within hybrids leads to novel phenotypes,
including transgressive segregation and heterosis, in which the hybrids
surpass its (homozygous) parents for growth and reproductive fitness.
The genetic and molecular basis of this non-additive mode of inheritance
is one major question that keeps us collecting diversity, inducing diversity,
crossing, genotyping, and last but not least, phenotyping. This serves to
draw the genomic picture underlying this phenomenon, as well as looking for
causative loci and genes underlying adaptive and agricultural phenotypes.
Next generation sequencing data and field/bench phenotype are integrated to
find these needles in the hay that make the difference.
The results of these studies should serve as a road map for unraveling
hitherto unknown mechanisms underlying crop productivity, as well as
understanding the possible role balancing selection plays in shaping and
maintaining genetic diversity under changing environments.
Recent Publications:
Fridman, E., Pleban, T. and Zamir, D. (2000) A recombination hotspot delimits a wild species QTL for tomato sugar content to 484-bp within an invertase gene. Proc. Natl. Acad. Sci. USA 97: 4718-4723.
Fridman, E., Liu, Y.S., Carmel-Goren, L., Gur, A., Shoresh, M., Pleban, T., Eshed, Y. and Zamir, D. (2002) Two tightly linked QTLs modify tomato sugar content via distinct physiological pathways. Mol. Genet. Genomics 266: 821-826.
Fridman, E. and Zamir, D. (2003) Functional divergence of a syntenic invertase gene family in tomato, potato and Arabidopsis. Plant Phys. 131: 603-609.
Fridman, E., Carrari, F., Liu, Y.S., Fernie, A. and Zamir, D. (2004) Zooming-in on a quantitative trait for tomato yield using wild species introgression lines. Science 305: 1786-1789.
Fridman, E. and Pichersky, E. (2005) Metabolomics, proteomics, genomics and identification of enzymes substrates. Curr. Opin. Plant Bio. 8: 242-248.
Fridman, E., Wang, J., Iijima, Y., Froehlich, J.E., Gang, D.R., Ohlrogge, J. and Pichersky, E. (2005) Metabolic, genomic and biochemical analyses of glandular trichome from the wild tomato species Lycopersicon hirsutum identify a key enzyme in the methylketone biosynthetic pathway. Plant Cell 17: 1252-1267.
Koeduka, T. , Fridman, E.*, Gang, D.R. *, Vasso, D.G. , Jackson, B.L., Kish, C.M., Orlova, I., , Spassova, S.M. , Lewis, N.G., Noel, J.P., Baiga, T.J., Dudareva, N., Pichersky, E. (2006) Eugenol and isoeugenol, characteristic aromatic constituents of spices, are biosynthesized via reduction of a coniferyl alcohol ester. Proc Natl Acad Sci USA 103: 10128-10133. (*Equal contribution).
Shemesh, K., Iijima, Y., and Fridman, E. (2007) Targeted and non-targeted mutagenesis of metabolic pathways in medicinal plants and herbs. Isr J Plant Sci 55: 115-123.
Hübner, S., Hffken, M., Oren, E., Haseneyer, G., Stein, N., Graner, A., Schmid, K., and Fridman, E. (2009) Strong correlation of the population structure of wild barley (Hordeum spontaneum) across Israel with temperature and precipitation variation. Mol Ecol 18: 1523-1536.
Ben-Israel, I., Yu, G., Austin, M.B., Auldridge, M., Nguyen, T., Bhuiyan, N., Schauvinhold, I., Noel, J.P., Pichersky, E. and Fridman, E. (2009) Multiple biochemical and morphological factors underlie the production of methylketones in tomato trichomes. Plant Phys 151(4):1952-1964 (cover paper)
Yu, G., Nguyen, T.H., Guo, Y., Schauvinhold, I., Auldridge, M., Bhuiyan, N., Ben-Israel, I., Iijima, Y., Fridman, E., Noel, J.P., Pichersky, E. (2010) Enzymatic functions of wild tomato Solanum habrochaites glabratum methylketone synthases 1 and 2. Plant Phys 154:67-77.
Gur, A., Osorio, S., Fridman, E., Fernie, A.R., Zamir, D. (2010) hi2-1, A QTL which improves harvest index, earliness and alters metabolite accumulation of processing tomatoes. Theor Appl Genet 121(8):1587-99
Hoffmann, T., Kurtzer, R., Skowranek, K., Kie?ling, P., Fridman, E., Pichersky, E., and Schwab, W. (2011) Metabolic engineering in strawberry fruit uncovers a dormant biosynthetic pathway. Metab Eng 13:527-531.
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