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August 2009
Leor Eshed Williams
Phone: +972 8 9489964
Fax: 972-8-948-9899
E-mail: williams@agri.huji.ac.il
Lecturer
Research Interests
Totipotency, plant cell plasticity, differentiation and regeneration.
Using genetic and genomic tools together with tissue culture.
Research Projects
Genetic networks regulating meristem development, pluripotency of the plant meristems,
transcription profiling of different cells at the shoot apical meristem.
Open positions
MSc, Ph.D and postDoc
List of Publications
Kim SY., Lee J., Eshed Williams L., Zilberman D., Sung ZR. (2012).
EMF1 and PRC2 Cooperate to Repress Key Regulators of Arabidopsis Development.
PLoS Genet. 8(3)
Ron M, Saez MA., Eshed-Williams L., Fletcher JC., McCormick S. (2010).
Proper regulation of a sperm-specific cis-nat-siRNA is essential for double
fertilization in Arabidopsis. Genes Dev. 15;24(10):1010-21.
Hsieh CU, Ibarra , Silva P, Zemach A, Eshed-Williams L, Fischer RL and Zilberman D. (2009).
Genome-wide demethylation of Arabidopsis endosperm. Science 12;324(5933):1451-4.
Williams, L., Fletcher, JC. (2005). Stem cell regulation in the Arabidopsis shoot
apical meristem. Curr Opin Plant Biol. 8(6):582-6.
Williams, L., Carles CC, Osmont KS, Fletcher JC. (2005).
A database analysis method identifies an endogenous trans-acting short-interfering RNA that targets the
Arabidopsis ARF2, ARF3, and ARF4 genes. Proc Natl Acad Sci USA. 5;102(27):9703-8.
Williams, L., Grigg SP, Xie M, Christensen S, Fletcher JC. (2005).
Regulation of Arabidopsis shoot apical meristem and lateral organ formation by microRNA miR166g and
its AtHD-ZIP target genes. Development. 132(16):3657-68
Williams, L., Zhao J, Morozova N, Li Y, Avivi Y, Grafi G. (2003).
Chromatin reorganization accompanying cellular dedifferentiation is associated with modifications of
histone H3, redistribution of HP1, and activation of E2F-target genes. Dev Dyn. ;228(1):113-20.
Zhao, J., Morozova, N., Williams, L., Libs, L., Avivi, Y. and Grafi G. (2001).
Two phases of chromatin decondensation during dedifferentiation of plant cells: distinction between
competence for cell fate switch and a commitment for S phase. J Biol Chem 22;276(25):22772-8.
Williams, L., and Grafi, G. (2000)
The RETINOBLASTOMA protein – a bridge to heterochromatin. Trends Plant Sci 5 (6): 239-240.
Avivi, Y., Lev-Yadun, S., Morozova, N., Libs, L., Williams, L., Zhao, J., Varghese, G. and
Grafi, G.(2000). Clausa, a tomato mutant with a wide range of phenotypic perturbations,
displays a cell type-dependent expression of the homeobox gene LeT6/TKn2.
Plant Physiol. 124(2):541-52.
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